Yes, a lot of them actually xD, the ones that most hurt for me:
- Charmander (last starter evolution I needed, then the event came)
- Machop (another 3 evolution I needed, in my town there was almost no Machop spawn since day 1, after I walked some km and hatched 2 from eggs, a park nearby became a Machop nest...)
- Grimer, all of us now why, a part from Lapras it was the last mon I needed to complete my dex, after I got Muk I hatched 2 in a row, then catch 2 wild Muks, lol
This last was 3 months ago, since then I have make Dragonite my buddy, despite having 3 Dragonites already Dratini candies will never be useless and won't change him until at least full gen2 comes or I hatch another Lapras or Snorlax (yes I still dream about it, my last rare hatch was back during halloween event..)